Chronic diseases are one of the most difficult challenges to the beginning of the twentieth century. Monitoring patients with chronic diseases, especially in chronic heart failure or diabetes mellitus, using telemedicine systems is a potential means for optimizing the management of these patients, even in elderly patients. The e-care project is developing an “intelligent” communicative platform enabling the home monitoring of patients with heart failure, using non-invasive sensors, with additional contextual information and patients’ profile.